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Genome-wide gene expression analysis in black South African women who develop gestational diabetes m

Genome-wide gene expression analysis in black South African women who develop gestational diabetes m

Posted on: 20 August 2014

To understand the impact of gestational diabetes on the foetus by investigating gene expression and DNA methylation to look for epigenetic perturbations that may lead to an unfavourable outcome in the offspring.


Pathophysiology and epidemiology  of peripartum cardiomyopathy

Pathophysiology and epidemiology of peripartum cardiomyopathy

Posted on: 14 August 2014

Cardiovascular diseases are a major cause of complications in pregnancy worldwide, and the number of patients who develop cardiac problems during pregnancy is increasing.


Lower levels of high-density lipoprotein cholesterol in urban Africans presenting with communicable

Lower levels of high-density lipoprotein cholesterol in urban Africans presenting with communicable

Posted on: 7 August 2014

An investigation into whether urban Africans displayed lower levels of arteroprotective high-density lipoprotein cholesterol (HDLC) when presenting with communicable versus non-communicable forms of heart disease (HD) as both acute infection and chronic inflammation reduce HDLC levels.


HIV can be transmitted from HIV-infected women to their babies

HIV can be transmitted from HIV-infected women to their babies

Posted on: 2 August 2014

HIV can be transmitted from HIV-infected women to their babies. The way this can happen is via transmission to your unborn child during pregnancy or delivery or during breastfeeding.


Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress

Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress

Posted on: 28 July 2014

Postpartum Akt activation is detrimental for the peripartum heart as it lowers anti-oxidative defence and in combination with low STAT3 conditions, accelerate cardiac inflammation and fibrosis. PRL and its cleaved 16 kDa form are central for Akt-induced PPCM, as indicated by the protection from the disease by PRL blockade.