News – Education

Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress

Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress

Posted on: 28 July 2014

Postpartum Akt activation is detrimental for the peripartum heart as it lowers anti-oxidative defence and in combination with low STAT3 conditions, accelerate cardiac inflammation and fibrosis. PRL and its cleaved 16 kDa form are central for Akt-induced PPCM, as indicated by the protection from the disease by PRL blockade.


Prestigious lecture series at Wits: cardiovascular disease in Africans and importance of lifestyle

Prestigious lecture series at Wits: cardiovascular disease in Africans and importance of lifestyle

Posted on: 28 January 2010

Although cardiovascular disease and its major component, heart disease, exists in epidemic proportions in Western developed countries, it is also an increasing problem in Africa, contributing to significant morbidity and premature mortality in vulnerable populations.


Burden of heart failure in Soweto – The Heart of Soweto Study

Burden of heart failure in Soweto – The Heart of Soweto Study

Posted on: 1 January 2008

Chris Hani Baragwanath Hospital services the 1.1 million black African community of Soweto, South Africa.